The TUBB3 Antibody (N-term) from MyBioSource.com is a Rabbit Polyclonal antibody to Beta III Tubulin, and TUBB3. This antibody recognizes Human, Mouse, Rat, Chicken/Bird, and Non-Human Primate antigen. The TUBB3 Antibody (N-term) has been validated for the following applications: ELISA, Flow Cytometry, Immunohistochemistry, and Western Blot.
Description
Beta III tubulin is abundant in the central and peripheral nervous systems (CNS and PNS) where it is prominently expressed during fetal and postnatal development. As exemplified in cerebellar and sympathoadrenal neurogenesis, the distribution of beta III is neuron-associated, exhibiting distinct temporospatial gradients according to the regional neuroepithelia of origin. However, transient expression of this protein is also present in the subventricular zones of the CNS comprising putative neuronal- and/or glial precursor cells, as well as in Kulchitsky neuroendocrine cells of the fetal respiratory epithelium. This temporally restricted, potentially non-neuronal expression may have implications in the identification of presumptive neurons derived from embryonic stem cells